Functional mapping of brain synapses by the enriching activity-marker SynaptoZip

Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.

Bibliographic Details
Main Authors: Mattia Ferro, Jacopo Lamanna, Maddalena Ripamonti, Gabriella Racchetti, Alessandro Arena, Sara Spadini, Giovanni Montesano, Riccardo Cortese, Vincenzo Zimarino, Antonio Malgaroli
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01335-4