A comprehensive review on promising anti-viral therapeutic candidates identified against main protease from SARS-CoV-2 through various computational methods

A comprehensive review on promising anti-viral therapeutic candidates identified against main protease from SARS-CoV-2 through various computational methods

Abstract Background The COVID-19 pandemic caused by SARS-CoV-2 has shown an exponential trend of infected people across the planet. Crediting its virulent nature, it becomes imperative to identify potential therapeutic agents against the deadly virus. The 3-chymotrypsin-like protease (3CLpro) is a c...

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Bibliographic Details
Main Authors: Ekampreet Singh, Rameez Jabeer Khan, Rajat Kumar Jha, Gizachew Muluneh Amera, Monika Jain, Rashmi Prabha Singh, Jayaraman Muthukumaran, Amit Kumar Singh
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
3CLpro
In silico
Inhibitors
Structure-based virtual screening (SBVS)
Ligand-based virtual screening (LBVS)
Drug-repurposing
Online Access:http://link.springer.com/article/10.1186/s43141-020-00085-z

Internet

http://link.springer.com/article/10.1186/s43141-020-00085-z

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