Topiramate-induced modulation of hepatic molecular mechanisms: an aspect for its anti-insulin resistant effect.

Topiramate is an antiepileptic drug known to ameliorate insulin resistance besides reducing body weight. Albeit liver plays a fundamental role in regulation of overall insulin resistance, yet the effect of topiramate on this organ is controversial and is not fully investigated. The current work aime...

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Bibliographic Details
Main Authors: Hanan S El-Abhar, Mona F Schaalan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359316?pdf=render