The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease

The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease

Sickle cell disease (SCD) is one of the most common inherited diseases in the world and the patients present notorious clinical heterogeneity. It is known that patients with SCD present activation of the blood coagulation and fibrinolytic systems, especially during vaso-occlusive crises, but also du...

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Bibliographic Details
Main Authors: F. Moreira Neto, D.M. Lourenço, M.A.E. Noguti, V.M. Morelli, I.C.P. Gil, A.C.S. Beltrão, M.S. Figueiredo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Sickle cell disease
SC hemoglobinopathy
Sickle hemoglobinopathies
Inherited hypercoagulation states
MTHFR polymorphism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001000004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001000004

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