NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

Abstract Background Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly investigated. Results In our studies, Overexpression of the Notch1 NICD p...

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Bibliographic Details
Main Authors: Qisheng Zuo, Chen Zhang, Kai Jin, Jin Jing, Changhua Sun, Mahmoud F. Ahmed, Jiuzhou Song, Yani Zhang, Guohong Chen, Bichun Li
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cell & Bioscience
Subjects:
Primordial germ cells
Spermatogonial stem cells
Notch signaling
RNA-seq
Transduction
Online Access:http://link.springer.com/article/10.1186/s13578-018-0238-y

Internet

http://link.springer.com/article/10.1186/s13578-018-0238-y

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