FGFR4 profile as a prognostic marker in squamous cell carcinoma of the mouth and oropharynx.

BACKGROUND: Fibroblast growth factor receptor 4 (FGFR4) is a member of a receptor tyrosine kinase family of enzymes involved in cell cycle control and proliferation. A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression...

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Main Authors: Roberta Lelis Dutra, Marcos Brasilino de Carvalho, Marcelo Dos Santos, Ana Maria da Cunha Mercante, Diana Gazito, Rafael de Cicco, Gencapo Group, Eloiza Helena Tajara, Iúri Drumond Louro, Adriana Madeira Álvares da Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511351?pdf=render