Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations With Phenotype

Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations With Phenotype

Epigenetics is an essential biological frontier linking genetics to the environment, where DNA methylation is one of the most studied epigenetic events. In recent years, through the epigenome-wide association study (EWAS), researchers have identified thousands of phenotype-related methylation sites....

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Bibliographic Details
Main Authors: Yuan Quan, Fengji Liang, Si-Min Deng, Yuexing Zhu, Ying Chen, Jianghui Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
DNA methylation
remodeling
gene level
SIMPO algorithm
phenotype-associated genes
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.597513/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.597513/full

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