Effective Reconstruction of Functional Urethra Promoted With ICG-001 Delivery Using Core-Shell Collagen/Poly(Llactide-co-caprolactone) [P(LLA-CL)] Nanoyarn-Based Scaffold: A Study in Dog Model

Effective Reconstruction of Functional Urethra Promoted With ICG-001 Delivery Using Core-Shell Collagen/Poly(Llactide-co-caprolactone) [P(LLA-CL)] Nanoyarn-Based Scaffold: A Study in Dog Model

Hypospadias and urethral stricture are common urological diseases which seriously affect voiding function and life quality of the patients, yet current clinical treatments often result in unsatisfactory clinical outcome with frequent complications. In vitro experiments confirmed that ICG-001 (a well...

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Bibliographic Details
Main Authors: Kaile Zhang, Xiaolan Fang, Jingjing Zhu, Ranxing Yang, Ying Wang, Weixin Zhao, Xiumei Mo, Qiang Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
urethral stricture
nanoyarn
Wnt signaling
urethral reconstruction
urethroplasty
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00774/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00774/full

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