Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection

Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection

Human rhinoviruses (HRV) are the most common cause of viral respiratory tract infections. While normally mild and self-limiting in healthy adults, HRV infections are associated with bronchiolitis in infants, pneumonia in immunocompromised patients, and exacerbations of asthma and COPD. The human cat...

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Bibliographic Details
Main Authors: Víctor Casanova, Filipa Henderson Sousa, Priyanka Shakamuri, Pavel Svoboda, Chloé Buch, Mathilde D'Acremont, Maria A. Christophorou, Jan Pohl, Craig Stevens, Peter G. Barlow
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
rhinovirus
virus
inflammation
peptide
LL-37
cathelicidin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00085/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00085/full

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