Orthopedic surgery-induced cognitive dysfunction is mediated by CX3CL1/R1 signaling
Abstract Background Postoperative pain is a common phenomenon after surgery and is closely associated with the development of postoperative cognitive dysfunction (POCD). Persistent pain and systemic inflammation caused by surgery have been suggested as key factors for the development of POCD. Fracta...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02150-x |