PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice

PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice

<p><i>Background:</i> Homocysteine (Hcy) is an independent cardiovascular risk factor; however, in diabetes, the role of tissue Hcy leading to cardiac dysfunction is unclear.</p> <p><i>Aims:</i> To determine whether tissue Hcy caused endothelial-myocyte unco...

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Bibliographic Details
Main Author: Walter E. Rodriguez, Utpal Sen, Neetu Tyagi, Munish Kumar, Gene Carneal, Deep Aggrawal, Justin Newsome, Suresh C. Tyagi
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v04p0236.htm

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http://www.biolsci.org/v04p0236.htm

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