Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity

Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity

Abstract Activity-dependent local protein synthesis is critical for synapse-specific, persistent plasticity. Abnormalities in local protein synthesis have been implicated in psychiatric disorders. We have recently identified the translin/trax microRNA-degrading enzyme as a novel mediator of protein...

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Bibliographic Details
Main Authors: Alan Jung Park, Mahesh Shivarama Shetty, Jay M. Baraban, Ted Abel
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Brain
Subjects:
Translin
Trax
Long-term potentiation
Long-term depression
Local protein synthesis
Hippocampal synaptic plasticity
Online Access:http://link.springer.com/article/10.1186/s13041-020-00691-5

Internet

http://link.springer.com/article/10.1186/s13041-020-00691-5

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