3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model

3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model

Abstract Background Sentinel lymph node metastasis is a common and early event in the metastatic process of head and neck squamous cell carcinoma (HNSCC) and is the most powerful prognostic factor for survival of HNSCC patients. 3-O-acetyloleanolic acid (3AOA), a pentacyclic triterpenoid compound is...

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Bibliographic Details
Main Authors: Jeon Hwang-Bo, Mun Gyeong Bae, Jong-Hwa Park, In Sik Chung
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
3-O-acetyloleanolic acid
Lymphangiogenesis
Lymph node metastasis
Oral cancer sentinel lymph node animal model
VEGF-A
Online Access:http://link.springer.com/article/10.1186/s12885-018-4630-0

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http://link.springer.com/article/10.1186/s12885-018-4630-0

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