Notch1 and Galectin-3 Modulate Cortical Reactive Astrocyte Response After Brain Injury

After a brain lesion, highly specialized cortical astrocytes react, supporting the closure or replacement of the damaged tissue, but fail to regulate neural plasticity. Growing evidence indicates that repair response leads astrocytes to reprogram, acquiring a partially restricted regenerative phenot...

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Bibliographic Details
Main Authors: Tais Novaki Ribeiro, Lina Maria Delgado-García, Marimelia A. Porcionatto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.649854/full