A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor

The LEAFY transcription factor is a master regulator of flower development in plants. Here the authors describe the structure of a LEAFY oligomerization domain and show that mutations that disrupt oligomerization alter its capacity to bind low affinity and poorly accessible target sites.

Bibliographic Details
Main Authors: Camille Sayou, Max H. Nanao, Marc Jamin, David Posé, Emmanuel Thévenon, Laura Grégoire, Gabrielle Tichtinsky, Grégoire Denay, Felix Ott, Marta Peirats Llobet, Markus Schmid, Renaud Dumas, François Parcy
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11222