Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status

Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status

In acute myeloid leukemia (AML), a low level of reactive oxygen species (ROS) is associated with leukemic stem cell (LSC) quiescence, whereas a high level promotes blast proliferation. ROS homeostasis relies on a tightly-regulated balance between the antioxidant and oxidant systems. Among the oxidan...

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Bibliographic Details
Main Authors: Hassan Dakik, Maya El Dor, Joan Leclerc, Farah Kouzi, Ali Nehme, Margaux Deynoux, Christelle Debeissat, Georges Khamis, Elfi Ducrocq, Aida Ibrik, Marie-José Stasia, Houssam Raad, Hamid Reza Rezvani, Fabrice Gouilleux, Kazem Zibara, Olivier Herault, Frédéric Mazurier
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antioxidants
Subjects:
Leukemia
AML
transcriptomics
NADPH oxidase
Online Access:https://www.mdpi.com/2076-3921/10/3/498

Internet

https://www.mdpi.com/2076-3921/10/3/498

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