Curcumin inhibits APOE4-induced injury by activating peroxisome proliferator-activated receptor-γ (PPARγ) in SH-SY5Y cells

Objective(s): The human apolipoprotein E4 (APOE4) is associated with various brain injuries and neurodegenerative changes. Curcumin is an active ingredient isolated from the root of turmeric and is believed to have therapeutic effects on neurodegenerative diseases. The aim of this study was to inves...

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Bibliographic Details
Main Authors: Minghui Wang, Jiejian Kou, Chunli Wang, Xiuying Yu, Xinmei Xie, Xiaobin Pang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_16838_625bbe4da902e21f28876e500d97112e.pdf