Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918.

The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day. Despite this disease burden, the evolutionary history of the A/H1N1 virus is not well understood, particularly whether th...

Full description

Bibliographic Details
Main Authors: Martha I Nelson, Cécile Viboud, Lone Simonsen, Ryan T Bennett, Sara B Griesemer, Kirsten St George, Jill Taylor, David J Spiro, Naomi A Sengamalay, Elodie Ghedin, Jeffery K Taubenberger, Edward C Holmes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2262849?pdf=render