Analyses of murine GBP homology clusters based on <it>in silico</it>, <it>in vitro </it>and <it>in vivo </it>studies

<p>Abstract</p> <p>The interactions between pathogens and hosts lead to a massive upregulation of antimicrobial host effector molecules. Among these, the 65 kDa guanylate binding proteins (GBPs) are interesting candidates as intricate components of the host effector molecule repert...

Full description

Bibliographic Details
Main Authors: Pfeffer Klaus, Wuerthner Jan, Beuter-Gunia Cornelia, Degrandi Daniel, Konermann Carolin, Kresse Alexandra, Beer Sandra
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/158