Tempol treatment shows phenotype improvement in mdx mice.

Considering potential Tempol effects on mdx muscle fibers, in this study we evaluated its effects on relevant dystrophic phenotypic characteristics, such as muscle degeneration, inflammatory process and angiogenesis, which as yet have not been investigated. Mdx mice were randomly assigned into three...

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Bibliographic Details
Main Authors: Túlio de Almeida Hermes, Rafael Dias Mâncio, Aline Barbosa Macedo, Daniela Sayuri Mizobuti, Guilherme Luiz da Rocha, Valéria Helena Alves Cagnon, Elaine Minatel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215590