Sperm-associated antigen 6 (Spag6) mutation leads to vestibular dysfunction in mice

Spag6 encodes an axoneme central apparatus protein that is required for normal flagellar and cilia motility. Recent findings suggest that Spag6 plays a role in hearing and planar cell polarity (PCP) in the cochlea of the inner ear. However, a role for Spag6 in the vestibule has not yet been explored...

Full description

Bibliographic Details
Main Authors: Xiaofei Li, Daogong Zhang, Lei Xu, Wenwen Liu, Na Zhang, Jerome F. Strauss, III, Zhibing Zhang, Haibo Wang
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000797