Analysis of Chronic Mild Stress-Induced Hypothalamic Proteome: Identification of Protein Dysregulations Associated With Vulnerability and Resiliency to Depression or Anxiety

Analysis of Chronic Mild Stress-Induced Hypothalamic Proteome: Identification of Protein Dysregulations Associated With Vulnerability and Resiliency to Depression or Anxiety

Chronic stress as a known risk factor leads to hyperactivity of the hypothalamus-pituitary-adrenal (HPA) axis in both depression and anxiety. However, the stress-induced dysfunction of the HPA axis in these disorders especially the common and unique molecular dysregulations have not been well-explor...

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Bibliographic Details
Main Authors: Weibo Gong, Wei Liao, Chui Fang, Yanchen Liu, Hong Xie, Faping Yi, Rongzhong Huang, Lixiang Wang, Jian Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
anxiety
chronic mild stress
depression
hypothalamus
quantitative proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.633398/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.633398/full

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