Role of mitochondrial damage in BPDE-induced inhibition of testosterone production in mouse Leydig cells

Objective To observe the effect of benzo[a]pyrene-r-7, t-8-dihydrodiol-t-9, 10-epoxide(±), (anti) (BPDE) on testosterone synthesis from mouse Leydig cells, and investigate the potential mechanism involved mitochondrial damage. Methods TM3 mouse Leydig cells were treated with various doses of BPDE fo...

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Bibliographic Details
Main Authors: YANG Wang, ZOU Peng, ZHANG Guowei
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-03-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201901001.htm