A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells

A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells

Background: Many microRNAs (miRs) are dysregulated in cancers, and aberrant miR expression patterns have been suggested to correlate with chemo-resistance of cancer cells. We aim to study the role of miR-30 family members in cisplatin-resistance of ovarian cancer cells. Methods: qRT-PCR was used to...

Full description

Bibliographic Details
Main Authors: Xi Han, Shuai Zhen, Zhongxue Ye, Jiaojiao Lu, Lijie Wang, Pan Li, Jie Li, Xia Zheng, Huijin Li, Wei Chen, Le Zhao, Xu Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ovarian cancer
Cisplatin resistance
microRNA
Methylation
Epithelial-mesenchymal transition
Online Access:http://www.karger.com/Article/FullText/460618

Internet

http://www.karger.com/Article/FullText/460618

Similar Items