Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer

Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer

Abstract Background 5-Hydroxymethylcytosine (5hmC) is converted from 5-methylcytosine (5mC) by a group of enzymes termed ten-eleven translocation (TET) family dioxygenases. The loss of 5hmC has been identified as a hallmark of most types of cancer and is related to tumorigenesis and progression. How...

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Bibliographic Details
Main Authors: Ding Peng, Guangzhe Ge, Yanqing Gong, Yonghao Zhan, Shiming He, Bao Guan, Yifan Li, Ziying Xu, Han Hao, Zhisong He, Gengyan Xiong, Cuijian Zhang, Yue Shi, Yuanyuan Zhou, Weimin Ci, Xuesong Li, Liqun Zhou
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Clinical Epigenetics
Subjects:
Bladder cancer
5-Hydroxymethylcytosine
Vitamin C
TET
Online Access:http://link.springer.com/article/10.1186/s13148-018-0527-7

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http://link.springer.com/article/10.1186/s13148-018-0527-7

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