Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines

Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines

Regulation of type-I interferon (IFN) production is essential to the balance between antimicrobial defence and autoimmune disorders. The human protein-coding gene ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains, previously C6orf106) was recently characterised as an inhibi...

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Bibliographic Details
Main Authors: Rebecca L. Ambrose, Aaron M. Brice, Alessandro T. Caputo, Marina R. Alexander, Leon Tribolet, Yu Chih Liu, Timothy E. Adams, Andrew G.D. Bean, Cameron R. Stewart
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Immunolgy
Inflammation
Infectious disease
Immune response
Viruses
Biochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020309592

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020309592

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