Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury

Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury

Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in plasma osmolality may impair kidney, cardiac, and immune function, and increase blood–brain barrier permeability. Thes...

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Bibliographic Details
Main Authors: Wojciech Dabrowski, Dorota Siwicka-Gieroba, Chiara Robba, Magdalena Bielacz, Joanna Sołek-Pastuszka, Katarzyna Kotfis, Romuald Bohatyrewicz, Andrzej Jaroszyński, Manu L. N. G. Malbrain, Rafael Badenes
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Clinical Medicine
Subjects:
osmolality
traumatic brain injury (TBI)
hypertonic saline
mannitol
osmolar gap
Online Access:https://www.mdpi.com/2077-0383/10/18/4141

Internet

https://www.mdpi.com/2077-0383/10/18/4141

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