Conserved and Divergent Mechanisms That Control TORC1 in Yeasts and Mammals

Target of rapamycin complex 1 (TORC1), a serine/threonine-protein kinase complex highly conserved among eukaryotes, coordinates cellular growth and metabolism with environmental cues, including nutrients and growth factors. Aberrant TORC1 signaling is associated with cancers and various human diseas...

Full description

Bibliographic Details
Main Authors: Yuichi Morozumi, Kazuhiro Shiozaki
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/1/88