The endothelin system in breast tumour - endothelial cell interactions

The role of endothelin-1 (ET-1) and its receptors (ET-RA and ET-RB) in tumour development and progression involves complex interactions. ET-1, produced by tumours and associated cells like endothelial cells, functions in an autocrine and paracrine manner to promote tumour angiogenesis. Thus, we h...

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Bibliographic Details
Main Authors: Tasnim Badat, Julia Botha, Strinivasen Naidoo
Format: Article
Language:English
Published: Academy of Science of South Africa 2011-01-01
Series:South African Journal of Science
Subjects:
Online Access:https://www.sajs.co.za/article/view/10079