Chronic abdominal vagus stimulation increased brain metabolic connectivity, reduced striatal dopamine transporter and increased mid-brain serotonin transporter in obese miniature pigs

Chronic abdominal vagus stimulation increased brain metabolic connectivity, reduced striatal dopamine transporter and increased mid-brain serotonin transporter in obese miniature pigs

Abstract Background/objective Changes in brain metabolism has been investigated thoroughly during unilateral cervical chronic vagal stimulation in epileptic or depressive patients. Bilateral stimulation of the abdominal vagus (aVNS) has received less attention despite the reduction in body weight an...

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Bibliographic Details
Main Authors: Charles-Henri Malbert, Mickael Genissel, Jean-Louis Divoux, Christine Henry
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Translational Medicine
Subjects:
Vagal stimulation
Bariatric surgery
SERT
DAT
Connectivity analysis
PET imaging
Online Access:http://link.springer.com/article/10.1186/s12967-019-1831-5

Internet

http://link.springer.com/article/10.1186/s12967-019-1831-5

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