Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals

Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals

Abstract Background C-Type Lectin Domain Family 3 Member B (CLEC3B), is down-regulated in serum and tumor tissues in different cancers including hepatocellular carcinoma (HCC). However, the functions of CLEC3B in HCC remains elucidated. The aim of this study is to analyze the roles of CLEC3B in HCC....

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Bibliographic Details
Main Authors: Wenjuan Dai, Yilin Wang, Tianxiao Yang, Jing Wang, Weicheng Wu, Jianxin Gu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cell Communication and Signaling
Subjects:
CLEC3B
Exosomes
Hepatocellular carcinoma
Endothelial cells
VEGF
AMPK
Online Access:http://link.springer.com/article/10.1186/s12964-019-0423-6

Internet

http://link.springer.com/article/10.1186/s12964-019-0423-6

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