IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway

IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway

We previously reported that astrocyte-derived proinflammatory cytokine interleukin (IL)-17A could aggravate neuronal ischemic injuries and strength autophagy both in oxygen-glucose deprivation (OGD)/reoxygenation (R)-treated neurons and peri-infarct region of mice with middle cerebral artery occlusi...

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Bibliographic Details
Main Authors: Ting Liu, Song Han, Qingqing Dai, Jiayin Zheng, Cui Liu, Shujuan Li, Junfa Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
ischemic stroke
IL-17A
autophagy
OGD/R
Src-PP2B-mTOR pathway
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02952/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02952/full

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