An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

Full description

Bibliographic Details
Main Authors: Hong-Li Hua, Fa-Zhan Zhang, Abraham Alemayehu Labena, Chuan Dong, Yan-Ting Jin, Feng-Biao Guo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/7639397