Metabolism of lithocholic acid in the rat: formation of lithocholic acid 3-O-glucuronide in vivo.
Milligram amounts of [3 beta-3H]lithocholic (3 alpha-hydroxy-5 beta-cholanoic) acid were administered by intravenous infusion to rats prepared with a biliary fistula. Analysis of sequential bile samples by thin-layer chromatography (TLC) demonstrated that lithocholic acid glucuronide was present in...
Main Authors: | JM Little, P Zimniak, KE Shattuck, R Lester, A Radominska |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1990-04-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520428299 |
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