Metabolism of lithocholic acid in the rat: formation of lithocholic acid 3-O-glucuronide in vivo.

Milligram amounts of [3 beta-3H]lithocholic (3 alpha-hydroxy-5 beta-cholanoic) acid were administered by intravenous infusion to rats prepared with a biliary fistula. Analysis of sequential bile samples by thin-layer chromatography (TLC) demonstrated that lithocholic acid glucuronide was present in...

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Bibliographic Details
Main Authors: JM Little, P Zimniak, KE Shattuck, R Lester, A Radominska
Format: Article
Language:English
Published: Elsevier 1990-04-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428299