CAG repeat variants in the POLG1 gene encoding mtDNA polymerase-gamma and risk of breast cancer in African-American women.

CAG repeat variants in the POLG1 gene encoding mtDNA polymerase-gamma and risk of breast cancer in African-American women.

The DNA polymerase-gamma (POLG) gene, which encodes the catalytic subunit of enzyme responsible for directing mitochondrial DNA replication in humans, contains a polyglutamine tract encoded by CAG repeats of varying length. The length of the CAG repeat has been associated with the risk of testicular...

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Bibliographic Details
Main Authors: Sami Azrak, Vanniarajan Ayyasamy, Gary Zirpoli, Christine Ambrosone, Elisa V Bandera, Dana H Bovbjerg, Lina Jandorf, Gregory Ciupak, Warren Davis, Karen S Pawlish, Ping Liang, Keshav Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3262786?pdf=render

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http://europepmc.org/articles/PMC3262786?pdf=render

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