Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

BACKGROUND Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS L. braziliensis-GFP was generated using Leish...

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Bibliographic Details
Main Authors: Matheus Silva e Bastos, Luciana Ângelo de Souza, Thiago Souza Onofre, Abelardo Silva Júnior, Márcia Rogéria de Almeida, Gustavo Costa Bressan, Juliana Lopes Rangel Fietto
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000200155&lng=en&tlng=en