Effect of the systemic administration of methylprednisolone on the lungs of brain-dead donor rats undergoing pulmonary transplantation

Effect of the systemic administration of methylprednisolone on the lungs of brain-dead donor rats undergoing pulmonary transplantation

OBJECTIVE: Most lung transplants are obtained from brain-dead donors. The physiopathology of brain death involves hemodynamics, the sympathetic nervous system, and inflammatory mechanisms. Administering methylprednisolone 60 min after inducing brain death in rats has been shown to modulate pulmonary...

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Bibliographic Details
Main Authors: Luiz Felipe Lopes Araujo, Arthur Rodrigo Ronconi Holand, Artur de Oliveira Paludo, Everton Franco Silva, Luiz Alberto Forgiarini, Luiz Felipe Forgiarini, Mariel Barbachan e Silva, Cristiano Feijo Andrade
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2014-02-01
Series:Clinics
Subjects:
Lung Transplantation
Brain Death
Experimental Model
Methylprednisolone
Oxidative Stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000200128&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000200128&lng=en&tlng=en

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