Local transformations of androgens into estradiol by aromatase P450 is involved in the regulation of prolactin and the proliferation of pituitary prolactin-positive cells.

Local transformations of androgens into estradiol by aromatase P450 is involved in the regulation of prolactin and the proliferation of pituitary prolactin-positive cells.

In previous studies we demonstrated the immunohistochemical expression of aromatase in pituitary cells. In order to determine whether pituitary aromatase is involved in the paracrine regulation of prolactin-producing pituitary cells and the physiological relevance of pituitary aromatase in the contr...

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Bibliographic Details
Main Authors: María José García Barrado, Enrique J Blanco, Marta Carretero Hernández, María Carmen Iglesias Osma, Manuel Carretero, Julio J Herrero, Deborah Jane Burks, José Carretero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4076335?pdf=render

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http://europepmc.org/articles/PMC4076335?pdf=render

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