Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression

p53 has functional roles in tumor suppression as a guardian of the genome, surveillant of oncogenic cell transformation, and as recently demonstrated, a regulator of intracellular metabolism. Accumulating evidence has shown that the tumor microenvironment, accompanied by inflammation and tissue remo...

Full description

Bibliographic Details
Main Authors: Ikuno Uehara, Nobuyuki Tanaka
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
p53
Online Access:http://www.mdpi.com/2072-6694/10/7/219