Pericardial Tamponade After Systemic Alteplase in Stroke and Emergent Reversal With Tranexamic Acid

Alteplase, or tissue plasminogen activator (tPA), lyses clots by enhancing activation of plasminogen to plasmin. Conversely, tranexamic acid (TXA) functions by inhibiting the conversion of plasminogen to plasmin, which inhibits fibrinolysis. TXA has proven safe and effective in major bleeding with v...

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Bibliographic Details
Main Authors: Cynthia Romero, Samuel Shartar, Michael J. Carr
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2020-02-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/7zt8c7w3