Anticancer and Multidrug Resistance-Reversal Effects of Solanidine Analogs Synthetized from Pregnadienolone Acetate

Anticancer and Multidrug Resistance-Reversal Effects of Solanidine Analogs Synthetized from Pregnadienolone Acetate

A set of solanidine analogs with antiproliferative properties were recently synthetized from pregnadienolone acetate, which occurs in Nature. The aim of the present study was an in vitro characterization of their antiproliferative action and an investigation of their multidrug resistance-reversal ac...

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Bibliographic Details
Main Authors: István Zupkó, Judit Molnár, Borbála Réthy, Renáta Minorics, Éva Frank, János Wölfling, Joseph Molnár, Imre Ocsovszki, Zeki Topcu, Tamás Bitó, László G. Puskás
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Molecules
Subjects:
solanidine analog
anticancer action
efflux pump
Online Access:http://www.mdpi.com/1420-3049/19/2/2061

Internet

http://www.mdpi.com/1420-3049/19/2/2061

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