Fractionated small cell‐free DNA increases possibility to detect cancer‐related gene mutations in advanced colorectal cancer

Fractionated small cell‐free DNA increases possibility to detect cancer‐related gene mutations in advanced colorectal cancer

Abstract Background and Aim Liquid biopsy is a method that can efficiently detect tumor genetic abnormalities from body fluids such as blood and urine. Detection sensitivity and the available number of mutations in cell‐free DNA (cfDNA) are limited. In this study, we develop a highly sensitive and c...

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Bibliographic Details
Main Authors: Yasuaki Ishida, Shinichi Takano, Shinya Maekawa, Tatsuya Yamaguchi, Takashi Yoshida, Shoji Kobayashi, Fumihiko Iwamoto, Toru Kuno, Hiroshi Hayakawa, Shuya Matsuda, Mitsuharu Fukasawa, Hiroko Shindo, Taisuke Inoue, Yasuhiro Nakayama, Daisuke Ichikawa, Tadashi Sato, Nobuyuki Enomoto
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:JGH Open
Subjects:
colorectal carcinoma
digital PCR
fractionated small cfDNA
liquid biopsy
next‐generation sequencing
Online Access:https://doi.org/10.1002/jgh3.12379

Internet

https://doi.org/10.1002/jgh3.12379

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