The Depolarization-Evoked, Ca2+-Dependent Release of Exosomes From Mouse Cortical Nerve Endings: New Insights Into Synaptic Transmission

The Depolarization-Evoked, Ca2+-Dependent Release of Exosomes From Mouse Cortical Nerve Endings: New Insights Into Synaptic Transmission

Whether exosomes can be actively released from presynaptic nerve terminals is a matter of debate. To address the point, mouse cortical synaptosomes were incubated under basal and depolarizing (25 mM KCl-enriched medium) conditions, and extracellular vesicles were isolated from the synaptosomal super...

Full description

Bibliographic Details
Main Authors: Guendalina Olivero, Francesca Cisani, Danilo Marimpietri, Daniela Di Paolo, Maria Cristina Gagliani, Marina Podestà, Katia Cortese, Anna Pittaluga
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
synaptosomes
exosomes
calcium dependency
glutamate release
GABAB receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.670158/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.670158/full

Similar Items