Kernel weighted least square approach for imputing missing values of metabolomics data

Abstract Mass spectrometry is a modern and sophisticated high-throughput analytical technique that enables large-scale metabolomic analyses. It yields a high-dimensional large-scale matrix (samples × metabolites) of quantified data that often contain missing cells in the data matrix as well as outli...

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Bibliographic Details
Main Authors: Nishith Kumar, Md. Aminul Hoque, Masahiro Sugimoto
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90654-0