Sex differences in the evolution of left ventricle remodeling in rats with severe volume overload

Abstract Background Aortic valve regurgitation (AR) results in left ventricle (LV) volume overload (VO) leading to its dilation and hypertrophy (H). We study a rat model of severe AR induced by puncturing one or two leaflets using a catheter. Most of our studies were conducted in male animals. Recen...

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Bibliographic Details
Main Authors: Elisabeth Walsh-Wilkinson, Marie-Claude Drolet, Marie Arsenault, Jacques Couet
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-020-01360-0