Rapid cell culture and pre-clinical screening of a transforming growth factor-β (TGF-β) inhibitor for orthopaedics

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMPs) utilize parallel and related signaling pathways, however the interaction between these pathways in bone remains unclear. TGF-β inhibition has been previously...

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Bibliographic Details
Main Authors: Kijumnuayporn Sandy, Liu Renjing, Yu Nicole YC, Mikulec Kathy, Peacock Lauren, Morse Alyson, Schindeler Aaron, McDonald Michelle M, Baldock Paul A, Ruys Andrew J, Little David G
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/105