JC virus mediates invasion and migration in colorectal metastasis.

INTRODUCTION:JC Virus (JCV), a human polyomavirus, is frequently present in colorectal cancers (CRCs). JCV large T-Ag (T-Ag) expressed in approximately half of all CRC's, however, its functional role in CRC is poorly understood. We hypothesized that JCV T-Ag may mediate metastasis in CRC cells...

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Bibliographic Details
Main Authors: Alexander Link, Sung Kwan Shin, Takeshi Nagasaka, Francesc Balaguer, Minoru Koi, Barbara Jung, C Richard Boland, Ajay Goel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2781631?pdf=render