Apo-9′-Fucoxanthinone, Isolated from Sargassum muticum, Inhibits CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase Pathway

Apo-9′-Fucoxanthinone, Isolated from Sargassum muticum, Inhibits CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase Pathway

Sargassum muticum (S. muticum) is a brown edible alga and widely distributed in Korea. This report was designed to evaluate the anti-inflammatory properties of apo-9′-fucoxanthinone (APO-9′) isolated from S. muticum on pro-inflammatory cytokine production. S. muticum extract (SME) exhibited signific...

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Bibliographic Details
Main Authors: Young-Sang Koh, Mi-Hee Ko, Jin-Won Hyun, Nam Ho Lee, Hee-Kyoung Kang, Eun-Sook Yoo, Tae-Heon Oh, Sung Chun Kim, Sohyun Kim, Zahid Manzoor, Doobyeong Chae
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Marine Drugs
Subjects:
Sargassum muticum
apo-9′-fucoxanthinone
activator protein-1
pro-inflammatory cytokine
ERK1/2
inflammation
Online Access:http://www.mdpi.com/1660-3397/11/9/3272

Internet

http://www.mdpi.com/1660-3397/11/9/3272

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