Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

High-grade serous ovarian cancer is the most common and aggressive ovarian cancer, with uncertain cell of origin. Here, the authors undertake a mass spectrometric analysis of 26 cancer cell lines and identify a protein signature that classifies ovarian cancer tissues into epithelial and mesenchymal...

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Bibliographic Details
Main Authors: F. Coscia, K. M. Watters, M. Curtis, M. A. Eckert, C. Y. Chiang, S. Tyanova, A. Montag, R. R. Lastra, E. Lengyel, M. Mann
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12645